ACE Axcel® Clinical Chemistry System For BioPharmaceutical, University, Academic, Government, and Other Translational Research Labs Optimize drug discovery research with the ACE Axcel clinical chemistry system. Easily evaluate, benchmark, sort, and monitor drug efficacy and safety effects on serum blood chemistries in the same animal. Make faster and better go/no go decisions for your drug candidates. Meet guiding principles of the 3 R’s for more ethical use of animals in drug discovery research. Sample specimens include serum, plasma, urine, CSF, homogeneous fluids, and tissue lysates. The ACE Axcel clinical chemistry system is... Innovative Low void volume and more data from fewer animals Flexible Open channel and new biomarker assay analysis for translational research center applications Efficient Up to 285 tests/hour with a 75-sample capacity load Reliable Accurate, reproducible data you can trust Compact Self-contained, perfectly small footprint ACE Axcel Instrument Features Micro sample cups allow the monitoring of drug efficacy and safety effects in the same animals (eliminate the need of large "n" of animals for serial blood collection) Self-contained system in a small footprint; no dedicated waste disposal, water line, or cooling unit required Disposable cuvettes provide the highest level of accuracy and eliminate the need for a water system Continuous sample loading of up to 75 samples, processing up to 285 tests/hour Perform single or panel tests from an extensive test menu Open reagent system enables custom assays Reagents are available to run the following assays: Hepatic Function Cardiovascular Function Renal Function and Disease (AKI/CKD/DKD) Alanine Aminotransferase (ALT) Aspartate Aminotransferase (AST) Serum Blood Urea Nitrogen (BUN) Albumin (ALB) Calcium (Ca++) Serum Creatinine (CREAT) Alkaline Phosphatase (ALP) Carbon Dioxide (CO2) Total Protein (TP) Aspartate Aminotransferase (AST) Cholesterol (CHOL) Non-Alcoholic Fatty Liver Disease/Steatohepatitis (NAFLD and NASH) and Diabetes Conjugated Bilirubin (Direct Bilirubin) (DBILI) Creatine Kinase (CK) Alanine Aminotransferase (ALT) Globulin (Total Protein-Albumin) (GLOB)* High Density Lipoprotein Cholesterol (HDL-C) Amylase (AMYL) Lactate Dehydrogenase (LDH) Iron (TIRON) Aspartate Aminotransferase (AST) Total Bilirubin (TBILI) Lactate Dehydrogenase (LDH) Cholesterol (CHOL) Electrolyte Assays Low Density Lipoprotein Cholesterol (LDL-C) Ferritin (FERITN) Calcium (Ca++) Magnesium (Mg++) Glucose (GLU) Chloride (CI-) Potassium (K+) Hemoglobin A1c (A1c) Direct TIBC (TIBC) Sodium (Na+) High Density Lipoprotein Cholesterol (HDL-C) Magnesium (Mg++) Triglycerides (TRIG) Lactate Dehydrogenase (LDH) Potassium (K+) Drug-Induced Liver Injury and Acute Liver Failure (DILI and ALF) Lipase (LIP) Sodium (Na+) Alanine Aminotransferase (ALT) Low Density Lipoprotein Cholesterol (LDL-C) Cholestatic Liver Disease, Primary Biliary Cirrhosis, and Primary Sclerosing Cholangitis (PBC/PSC/PFIC) Alkaline Phosphatase (ALP) Total Thyroxine (T4) Alanine Aminotransferase (ALT) Aspartate Aminotransferase (AST) Triglycerides (TRIG) Alkaline Phosphatase (ALP) Conjugated Bilirubin (Direct Bilirubin) (DBILI) Uric Acid (UA) Bile Acids (BILEAC)** Creatine Kinase (CK) Conjugated Bilirubin (Direct Bilirubin) (DBILI) Lactate Dehydrogenase (LDH) Gamma-Glutamyl Transferase (GGT) Total Bilirubin (TBILI) Total Bilirubin (TBILI) Additional assays are available via open channels. *Derived tests **For veterinary and research/investigational use only. Not for use in diagnostic procedures.
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